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Effect of Pregnant Cows Urine on Follicular Dynamics in Female Wistar Albino Rats

Kruthika, P.R., Veena, T., Nararana Swamy, M., Honnappa, T.G.Naranana Swamy, H. D. Sridhar N. B..


An experiment was conducted to evaluate the effects of pregnant cow urine, known to contain estrogen, on follicular dynamics in female Wistar albino rats. The rats were reared from twenty day of age for about 60 days in four groups consisting of six rats in each group. First trimester pregnant cow urine and last trimester pregnant cow urine was administered orally at a dose of 15 ml/ kg b.w to Group III and Group IV respectively. Group II was orally administered with 15 ml / kg b.w of non-pregnant cow urine whereas Group I was orally administered with distilled water which served as control. The average number of surface follicles in left ovary was significantly high in Group IV compared to Group I and Group II. The mean number of small preantral (Class I) follicles significantly increased in Group III and Group IV (P

Key words: Pregnant Cow Urine, Estrogen, Female Wistar Albino Rats, Folliculogenesis

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