Familial multiple lipomatosis (FML) is a very rare benign condition with the prevalence of 0.002% in general population (1:50,000). It is inherited as an autosomal dominant disease. It is more prevalent in men. It is characterized by multiple, soft-tissue swellings on hand, forearm, thigh, and abdomen. We are presenting this case of a 24-year-old man with the clinical and cytological pictures of FML with a family history to put more emphasis on its differential diagnosis of multiple symmetric lipomatosis and the use of fine needle aspiration cytology as a definitive diagnostic tool for these soft-tissue lesions.
Familial multiple lipomatosis, FNAC