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Histomorphological analysis of nonneoplastic skin lesions

Piyush G Vaghela, Bharti M Jha.

Abstract
Background: Nonneoplastic skin lesions include various skin conditions that have different histomorphological features. Many of nonneoplastic skin lesions are diagnosed by dermatologist but some others need biopsy and histopathological evaulations. Histopathological evaluation has synergistic role for diagnosis of skin disease.

Objective: To study the histopathology of various nonneoplastic skin lesions, to correlate histopathological diagnosis with clinical diagnosis and to study age, sex incidence in various nonneoplastic skin lesions.

Materials and Methods: Total 100 cases were studied. Sample is in the form of skin biopsies and staining was done with routine Hematoxylin-Eosin stain and special stains.

Results: Of the 100 cases of nonneoplastic skin lesions, inflammatory disease of the dermis and epidermis were most common (51%), followed by infectious disease of skin (25%), Vesiculobullous lesions (22%) and nonneoplastic disease of hair (2%). Of these 100 cases, there were 52 males and 48 females, and their ages ranged from 7 to 70 years. The most common age range of presentation being 2130 years (29%). Most common presentation was seen in males (52%) and most common site was back (31%).

Conclusion: Clinicohistopathological correlation is very important in the diagnosis of nonneoplastic skin disorders rather than considering either of them alone.

Key words: Nonneoplastic skin lesions, special stains, histomorphology



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