Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Article

J App Pharm Sci. 2015; 5(12): 111-116

In-vitro antioxidative potential of methanolic aerial extracts from three ethnomedicinal plants of Assam: A Comparative Study

Kabita Mahato, Bibhuti Bhusan Kakoti, Sudarshana Borah, Mritunjay Kumar.

Antioxidants are the substances that neutralize free radicals or their actions. The traditional antioxidant phytochemicals from plants have been reported to inhibit the propagation of free radical reactions and to protect the human body from disease. The use of synthetic antioxidants has always been questioned because of their toxicity therefore researches are being carried out on plants nowadays to bring out the potent natural antioxidants. With this intent three ethnomedicinal plants of Assam viz., Calamus leptospadix Griff., Heliotropium indicum Linn., Lasia Spinosa Lour. were explored with a view to evaluate their in-vitro antioxidative potentials. The methanolic aerial extracts were studied for phytochemical analysis and antioxidative properties by different in-vitro assays: DPPH radical scavenging method, Nitric oxide radical scavenging activity, Hydrogen peroxide radical scavenging activity, Total phenolic content and Total flavonoid content. The percentage of inhibition was calculated by comparing the absorbance values of the control and test samples. The study conducted revealed that methanolic extract of Calamus leptospadix (CL) exhibited the highest DPPH radical scavenging activity (IC50 value of 29 3.24 μg/ml), Nitric oxide radical scavenging activity (233.33 3.54 μg/ml), Total phenolic content (8.02 0.32 μg/ml expressed as gallic acid equivalents) and Total flavonoid contents (61.71 1.16 μg/ml expressed as quercetin equivalents). Methanolic extract of Lasia spinosa (LS) showed highest hydrogen peroxide radical scavenging activity (IC50 value of 221.89 2.14 μg/ml). The results obtained in the present study indicate that aerial parts of Calamus leptospadix have potent, Lasia spinosa have moderate and Heliotropium indicum (HI) have mild antioxidant and free radical scavenging activity.

Key words: Calamus leptospadix Griff., Lasia spinosa Lour., Heliotropium indicum Linn., Antioxidative potential, DPPH

Similar Articles

Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease.
Goulding SR, Anantha J, Collins LM, Sullivan AM, O'Keeffe GW
Neural regeneration research. 2022; 17(1): 38-44

Study on the antioxidative mechanism of tocopherol loaded ethyl cellulose particles in thermal-oxidized soybean oil.
Liu Y, Ma X, Li J, Fan L, Huang S
Carbohydrate polymers. 2022; 276(): 118734

Effects of selenium-containing compounds on Cu/Zn-induced neuronal cell death and potential application as therapeutic agents for neurological diseases.
Tanaka KI, Shimoda M, Kawahara M
Neural regeneration research. 2022; 17(2): 311-312

Structure reorganization of cellulose hydrogel by green solvent exchange for potential plastic replacement.
Shu L, Zhang XF, Wang Z, Yao J
Carbohydrate polymers. 2022; 275(): 118695

SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology.
Marques RF, Duncan KE
Neural regeneration research. 2022; 17(2): 266-270

Full-text options

Latest Statistics about COVID-19
• pubstat.org

Add your Article(s) to Indexes
• citeindex.org

Covid-19 Trends and Statistics
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.

ScopeMed Web Sites