In pediatric patients, Coronavirus disease-19 (COVID-19) presents usually without symptoms or with mild to moderate COVID-19. However, infants may present with more severe diseases, leading to even respiratory failure. COVID-19 may adversely affect the course of congenital heart disease (CHD) and vice versa in neonates and small infants. There is limited data about confirmed COVID-19 cases with CHD in neonates and early infancy. A newborn infant with confirmed COVID-19 was admitted to the Department of Neonatology of Chittagong Medical College Hospital. The case presented with C-Transposition of great arteries, superior-inferior ventricles, large upper muscular VSD with reverse shunt, large ASD with a left to right shunt, moderate right AV valve regurgitation (MR), and severe pulmonary hypertension. The newborn infant was isolated and was treated with antibiotics and cardiac drugs, along with supportive care. Ultimately, the infant deteriorated and expired. A newborn infant might be infected with COVID-19 even if a history of such infection in parents and caregivers is not found. Early identification of COVID-19 in neonates with CHD is essential for planning treatment, including limiting its transmission in the community.
Key words: Keywords: Newborn infant, COVID-19, SARS-CoV-2, RT-PCR assay, Congenital heart disease.
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