Hyperlipidemia is a major, modifiable risk factor for atherosclerosis and cardiovascular disease, including coronary heart disease. Daily intake of coconut oil increases serum HDL cholesterol, produces very little free radicals, is rapidly absorbed, oxidized and does not deposit in the body. In order to add up to these benefits, different types of coconut oils were blended with Vyosakatvivaradi, a classical Ayurvedic formulation. . Four different coconut oil extracts [VCO (virgin coconut oil), TCO (Traditional coconut oil), CCO (Commercial coconut oil), TCO + Coconut Milk + HERBS] of Vyosakatvivaradi formulation were prepared and their preventive and therapeutic hypolipidemic effects were studied in wistar rats. The medicated oil extract TCO + Coconut Milk + HERBS and CCO + HERBS showed encouraging therapeutic and preventive effects on hyperlipidemia. However, the oil extract TCO + Coconut Milk + HERBS is observed to be better than the oil extract CCO + HERBS. The oil extracts VCO + HERBS and TCO + HERBS exhibited moderate hypolipidemic action and their effect at different dose levels needs to be further evaluated.
Key words: Hyperlipidemia, coconut oil, coconut milk, Ayurveda