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Original Research

Effects of Prolonged Fasting on Sperm Count

Seriki A Samuel, Adebayo O Francis, Atsukwei Denen, Odetola O Anthony.

Background and Aim: In Nigeria, like in many other parts of the Africa and the world, people embark on fasting for various reasons; medical, spiritual, experimental, etc. Some even engage in prolonged fasting for a period of 30 days, 40 days, 50 days, or even longer. Prolonged fasting, as it were, has been observed to have various effects on some physiological parameters of the body. The current study reports on the effects such prolonged fasting has on semen profiling in mice, with particular emphasis on sperm count, and how it consequently affects fertility in the male. Method: Twenty (20) male mice used for the research were grouped into two. While mice in Group 1 were fasted for 12 hours per day for 30 days during which they were denied access to feeds and water, mice in Group 2 (control) were allowed free access to feeds and water throughout the period of the 30 days. At the end of the period, the semen from both groups were separately collected and analyzed, with emphasis on the sperm count. Results: The results showed that sperm count in the fasted group significantly (p

Key words: fasting, sperm count, spermatogenesis, sertoli cell, caloric restriction

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