Objective: Review postgraduate clinical trials on effectiveness of Ayurvedic
medicaments for Diabetic polyneuropathy. Methods: Electronic searches and Hand search strategies
were used to identify studies. The quantitative analysis is depicted in PRISMA chart. The
Methodological quality was assessed by using JADAD score. The Population included in the
study, Interventions used, with or without Control, and Outcome measures are presented in Table
of PICO analysis. The results of outcome measures were summarized under Primary & Secondary
end points. Results: Hand Searches procured six theses out of 14 researches done in post graduate
sector. Electronic searches revealed abstracts of two DHARA articles, three from PUBMED and
Med know and one from AYU journal. Conclusion: Among six clinical studies Niranjan 2011 stood
apart in methodological precision with Jadad score four out of five. Results were better when
combined with internal than use of external medicaments alone. The electrophysiologically beneficial
effects of Bhunimbaadi choorna by Nisha 2007 propose hope for drugs showing probable action
on nerve regeneration. Dashamoola used in various forms like dashamoola ghana vati, dashamoola
qwatha, dashamoola rasayana compound, showed statistically significant results compared to
others. As dashamoola is vatahara, efficacy of drug implies the role of vata in the very pathology
of DPN.
Key words: Diabetic peripheral neuropathy, Diabetic neuropathy, Distal Symmetric
Polyneuropathy, Madhumeha, Madhumehajanya Upadrava .
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