Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



Evaluation of seroprevalence of HbsAg infection among blood donors in a tertiary-care hospital

Praveen Gowda, Rajashekar HK.

Abstract
Background: Hepatitis B infection is a serious global and public health problem. Hepatitis B is one among the transfusion-transmissible infections. Hepatitis B virus (HBV) is a DNA virus that causes acute and chronic liver diseases. Transmission of infection occurs through blood transfusion, needles, body fluids, and sexual intercourse. The clinical diagnosis of carrier state of HBV is commonly done by the detection of hepatitis B surface antigen (HBsAg) in the serum.The prevalence of this infection differs across the globe. The preventive strategies can be accomplished by analyzing the trends in seroprevalence.

Objective: To assess the seroprevalence of HBsAg among blood donors attending the blood bank of a tertiary-care hospital.

Materials and Methods: The study was conducted at the blood bank of Hassan Institute of Medical Sciences (a tertiary-care hospital), Hassan, Karnataka, India. In this retrospective study, healthy blood donors, over a period of 3 years from 2011 to 2013, were assessed. The blood donors were categorized as voluntary and replacement donors. Blood samples from donors were subjected to serological tests for the detection of HBsAg through ELISA-based assay.

Result: A total of 11,894 blood donors were studied. Seventy-four (0.62%) cases were positive, which comes under the “low prevalence (

Key words: HBsAg, seroprevalence, blood donors, hepatitis B virus



Share this Article


Advertisement
American Journal of Physiology, Biochemistry and Pharmacology

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.