The impact of different doses of intrathecal dexmedetomidine used as adjuvant to hyperbaric prilocaine in short ambulatory procedures under spinal anaesthesia: a randomized controlled study.

Anaesth. pain intensive care. 2024; 28(4): 0-0

Eslam Gamal Biekhet, Hesham Elazzazi, Wael Hussein, Mohamed Zedan, Bassant Mohamed Abdelhamid.

Abstract
Objective: This study aimed to determine the most effective dose of dexmedetomidine as an adjuvant to prilocaine in spinal anaesthesia. Methods: Sixty-nine adult patients (21 to 65 years) scheduled for elective surgeries under spinal anaesthesia were included in the study. Patients received spinal anesthesia with 3ml of Prilocaine and 0.5 ml dexmedetomidine of dose according to randomization of 5,10 and15 µg (D5, D10 and D15 respectively). Time of the first request of analgesia was set as a primary outcome. Results: Time of the first request of rescue opioid was significantly shorter in D5 group (8± 6 hrs.) compared to D15group (21± 4 hrs.) (P value Key words: Intrathecal Dexmedetomidine, Hyperbaric Prilocaine, Ambulatory Surgery, Spinal Anaesthesia.