Home|Journals|Articles by Year

Directory for Medical Articles
 

Original Research

J Res Educ Indian Med . 2009; 15(1): 39-44


PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel.


Abstract

The methanolic extract of Hemidesmus indicus Linn. (MEHI) roots were evaluated for its psychopharmacological activities in several experimental models using Swiss albino mice and Spargue dawley rats. The MEHI was found to cause significant reduction in spontaneous activity, and decreases in exploratory behavioral profiles by the Y-maze and head dip test. It also showed reduction in muscle relaxant activity by rotarod; 30° inclined screen and traction tests, as well as significantly potentiated the phenobarbitone sodium induced sleeping time in the doses examined (200, 400 and 600 mg/kg body wt.). All the results were compared with respective controls for the evaluation of significance. Keywords: Y-maze test, Head dip test, Relaxant activity, Traction tests, Tranquilizer, Hemidesmus indicus Linn., Medicinal plants, Ayurvedic medicine.






Full-text options


Share this Article



Online Article Submission
• ejmanager.com







eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.