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Original Research

RMJ. 2015; 40(4): 371-374

Platelet count/splenic size ratio as a non-invasive parameter to predict the presence of esophageal varices in cirrhotics

Kausar Malik, Faiza Batool, Shazia Amir Khan, Zain ul Amir.


Objectives: To compare platelet count/splenic size ratio between patients with esophageal varices and without esophageal varices.
Methodology: It was cross-sectional study conducted at the department of Medicine Fauji Foundation Hospital, Rawalpindi, Pakistan and the time period was 6 months. During 6 months of study 60 patients with cirrhosis of liver were studied. These patients were evaluated for the chronic hepatitis B and C, ascites and splenic size by abdominal ultrasound, albumin, prothrombin time, complete blood count including platelet count and liver functions test. It was determined if the platelet count/ splenic size ratio between the two groups was different or not.
Results: Out Of 60 patients included in the study 53(88.3 %) were females, 7 (11.7 %) were males .The mean age was 52 years. All patients were hepatitis C positive. Ascites was present in 14 (23.3%) patient. varices were present in 40 (66.7%) patient, while it was absent in 20 (33.3%). The mean platelet count / splenic size ratio in patients with esophageal varices and without esophageal varices was found to be significantly different (p=0.000)
Conclusion: Platelet count / splenic size ratio in patients with esophageal varices and without esophageal varices is different.

Key words: Esophageal varices, cirrhosis, splenic size

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