cardiovascular diseases is currently one of the most important health issues.Chest pain is one of the most common disorders due to cardiovascular diseases that can be a warning sign for myocardial infarction.Chest pain can be due to heart and otherwise diseases. Bioactive compounds or medicinal herbs are a rich source of antioxidant compounds, biologically active ingredients, phenols, and other substances that inhibit oxidative stress and reduce free radicals through certain mechanisms, and therefore prevent cardiovascular diseases and reduce chest pains.These plants play the role of the traditional medicine in the treatment and prevention of cardiovascular diseases and other disorders affecting myocardial and vascular tissues.Some of the most important medicinal herbs have been addressed for their efficacy and action mechanisms in this article.Based on the results obtained from the review of numerous articles indexed in the databases ISI, Scopus, PubMed, Google Scholar, etc., a number of plants have been reported to be used for the treatment and prevention of cardiovascular diseases and chest pain due to cardiac disease, including Curcuma longa,Panax, Coptis, Sophora flavescens, Calendula officinalis, Carthamus tinctorius, Tripterygium wilfordi, Astragalus, Salvia miltiorrhiza, Ampelopsis grossedentata, Pseudotsuga menziesii, Vitis vinifera, Passiflora, Styphnolobium japonicum, Citrus, grapefruit, Allium sativum. Pharmacological studies have also investigated the therapeutic effects of medicinal herbs, and also their clinical effects and the use of their active ingredients in the production of useful natural drugs.The results of phytochemical investigations on these plants have shown that the most important compounds of the plants include total flavonoids and phenolics, steroids, Alkaloids, linoleic acid, adiponectin, flavonoids and phenolics, Myricitrin, Nobiletin, flavonoids ,limonoids, Naringin, Alliin, Alkaloids, isoquinoline alkaloids berberine, palmatine, and coptisine , gallic acid, rutin and saponin,ec. Due to main active ingredients and flavonoids of these plants, they can be used to produce natural drugs that reduce cardiovascular diseases and thus chest pain due to cardiac diseases, and therefore relieve the suffering of patients.
Key words: Chest Pain, Cardiovascular Disease, medicinal herbs, Phytotherapy