A total of one hundred and twenty rats and 200 mice were investigated during the present study to identify the helminth parasites of laboratory animals purchased from Abu rawash area, Giza, Egypt. The collected obtained helminthes were Hymenolepis (H.) nana, H. diminuta, Syphacia (S.) muris, and cyst of Strobilocercus fasciolaris (Cysticercus fasciolaris) in rats and H. nana, S. obvilata, Aspiculuris (A.) tetraptera and Strobilocercus (S) fasciolaris (Cysticercus) in mice. The common worm infection in rat was H. diminuta (25%) while in mice it was S. obvilata (55%). Infection of cats by the obtained Strobilocercus cysts gave adult worms of Taenia (T.) taeniaeformis after 55 days post-infection. Treatment of H. nana infected rats with single dose of Zanide (15 mg oxyclozanide and 7.5 mg levamizole per kg body weight) completely eradicated H. nana infection after one week post treatment. However, treatment of the infected rats with single dose of alzental (albendazole, 32 mg / kg body weight) was not efficient in H. nana worm elimination, but led only to an increase in H. nana egg output then decrease in number.
Key words: Helminth Parasitic Infection, Hymenolepis nana.
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