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Egypt. J. Exp. Biol. (Zoo.). 2012; 8(2): 335-340


ASSESSMENT OF SOME SEROLOGICAL TESTS FOR DIAGNOSIS OF TONSILLITIS CAUSED BY B-HEMOLYTIC STREPTOCOCCI IN RAMADI, IRAQ

Mothana A. AL-Zobaei Alaa A. AL –Khafaji Samera M. AL-Khalifawi.




Abstract

The main objective of the present study was to evaluate the performances of five serological assays Anti-Streptolysin O Titer, (ASOT), C Reactive Protein (CRP), Rheumatoid Factor (RF), Systemic Lupus Erthymatous (SLE), Infectious Mononucleosis (lM) tests for the diagnosis of tonsillitis due to beta hemolytic streptococci in AL-Ramadi (west of Iraq). One hundred ninety one tonsillitis patients were included in this study. They were attending department of ENT in Al Ramadi General Hospital in Iraq during the period from April 2008 to February 2009. Serum samples were taken from each one. Patients were classified into three groups; first one consists of 109 patients with recurrent tonsillitis, second consists of 45 patients with chronic tonsillitis and third consists of 37 patients with recurrent acute tonsillitis. In addition, twenty serum sample of healthy control group were included. There was a high titer of antibodies against Streptolysin O (ASOT) test in patients with a recurrent, chronic, recurrent acute tonsillitis due to beta-hemolytic streptococci, whereas the responses rates were markedly very low using other serological tests. The present study confirmed that the anti-Streptolysin O test (ASOT) is recommended for detection group A beta hemolytic streptococci (GBHS) among the patients with tonsillitis.

Key words: Beta-hemolytic streptococci, Serological assays






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