Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



A study on antibiotic resistance pattern of Escherichia coli isolated from urine specimens in Eastern India

Jayanti Ray, Rudrajit Paul, Abhik Haldar, Sagnic Mondol.

Abstract
Background: Antimicrobial resistance is an emerging threat in today’s world. Most of the common pathogens are demonstrating significant resistance to commonly used drugs. Escherichia coli (E. coli) is one of the most common bacterial pathogens in India. There are recent reports of high level of antibiotic resistance in E. coli. This will affect the treatment of common conditions such as urinary infection. This is a public health crisis for low- and middle- income countries such as India, as higher antibiotics will cause strain on the already restricted health budget. However, to curb the problem, there is need of clinical data on the prevalence of resistance.

Objective: This cross-sectional study was aimed at generating primary data on the prevalence of antibiotic resistance in E. coli in a sample population from Eastern India.

Materials and Methods: This study was carried out in a tertiary care hospital of Eastern India. Adult patients presenting with urinary tract infection (UTI) were included. Clean catch midstream urine sample was collected and cultured under aerobic conditions. Antibiotic sensitivity was tested by disk diffusion method after liquid culture. Standard descriptive statistical methods were used. Microsoft Excel was used for arranging the data.

Result: There were 32 patients in the study with male:female ratio of 10:22. Almost half (47%) of the specimens were resistant to ceftriaxone. Aminoglycoside resistance was found in 25% of the organisms. Fluoroquinolones resistance was also very high with 60% resistant to norfloxacin. E. coli specimens of 78% (n = 25) were multidrug resistant.

Conclusion: Our results give some preliminary data on antibiotic resistance pattern of E. coli in this region. This will help in the choice of antibiotics for common conditions such as UTI. However, bigger multicentric studies are needed.

Key words: Antibiotic, urine, Escherichia coli, fluoroquinolones, resistance


Full-text options

Full-text Article


Share this Article


Readers of this article also read the following articles
»Applied Medical Research (AMR) is starting
»A Study on Menstruation and Personal Hygiene among Adolescent Girls of Government Medical College, Solapur
»Our experience in nerve sparing laparascopic radical hysterectomy in treatment of early stage cervical cancer
»Iron deficiency and Helicobacter pylori infection
»Specific Implementation of Electronic Medical Record in Pediatrics Practice
»Assessment of autonomic function with heart rate turbulence and heart rate variability in young obese patients
»Incidence and Mortality of Liver Cancer and their Relationship with the Human Development Index in the World
»Assessment of patients’ understanding of the use of dispensed medications at a tertiary care hospital of central Gujarat
»Impact of Refresher Training on Knowledge Regarding Tuberculosis among Health Workers of West Bengal
»Relationship between self-esteem, social appearence anxiety, depression and anxiety in adolescent and young adult women
»Morphological Characteristics of Hassawi Donkey, Eastern Province, Saudi Arabia



Advertisement
American Journal of Preventive Medicine and Public Health

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.