Home|Journals|Articles by Year|Audio Abstracts

Original Research

Musa sapientum with exercises attenuates hyperglycaemia and pancreatic islet cells degeneration in alloxan-diabetic rats.

Adelaja Abdulazeez Akinlolu, Bamidele A Salau, Martins Ekor, Jubril Otulana.


Aim: We tested the hypothesis that administrations of methanolic extracts of Musa sapientum sucker (MEMS) with exercises attenuated hyperglycaemia in alloxan-diabetic rats.
Methods: Forty adult male rats were divided into equal eight groups. Normoglycaemic Group A was Control. Alloxan (180 mg/kg, i.p.) was administered to rats in Groups B – H to induce diabetes. Group B (diabetic control) received physiological saline. Groups C - H received MEMS (5 mg/kg), MEMS (10 mg/kg), MEMS (5 mg/kg) + exercises, MEMS (10 mg/kg) + exercises, Glibenclamide (5mg/kg) and Exercises only respectively. Changes in body weight, blood glucose levels (BGL) and pancreatic histology were evaluated during or at the end of experiment. Bodyweights and BGL of rats were expressed as mean ± standard deviation and analyzed using the statistical software program SPSS 15. Statistical comparisons were done using the Student’s t-test for unpaired samples. Differences between groups were determined as significant at P values ≤0.05.
Results: Significantly (p

Key words: Musa sapientum, alloxan, hyperglycaemia, pancreatic islet cells, rats

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.