Activity of ten different antibacterial agents commonly used in treatment of urinary tract infections (UTI) at AL-Batnan Medical Centre, Tobruq-Libya was studied against 8 different bacterial species isolated from 718 UTI patients, during 2004 - 2008. The study of the antibacterial sensitivity / resistance pattern indicated that UTI caused by (E. coli , Klebsiella pneumoniae, Staphyloccus epidermidis ,Staphyloccus aureus , Proteus mirabilis) isolates showed relatively a high to moderate rate of sensitivity to ciprofloxacin (77.6%) , amoxicillin (67.7%), nitrofurantoin (65.9%) and ceftrixone (58.5%). While Enterococcus faecalis isolates showed sensitivity to amoxicillin (70.2%), naldixic acid (60.3%) with a low rate of sensitivity to ampicillin (9.2%). The drug of choice to the Pseudomonas aeruginosa isolates was ciprofloxacin which revealed (87.5% sensitivity), while the other antibacterial agents failed completely or succeeded with low percentage in inhibition of Pseudomonas aeruginosa isolates growth. The study also revealed a noticeable increase in UTIs between 2004 and 2008 with a high rate of infections in children and females, with a prevalence of E. coli as a most common causative agent of UTI.
Key words: Antibacterial agents, sensitivity tests, urinary tract infections isolates
|
