The present study investigated the antibacterial activities of some seaweeds (Ulva lactuca, Laurencia optusa, and Turbinaria triquatra) collected from Red Sea coast-Egypt. Ethanol crude extracts of these macroalgae, as well as their fractions (oleic acid, palmitic acid, fucoxanthin and fucosterol which, extracted from T. triquatra) with five different concentrations were tested against most nosocomial bacteria, such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa (Urinary tract infection (UTI), Bacillus cereus, Bacillus subtilis and Staphylococcus aureus (Hospitalized infection) using disc diffusion method. The highest antibacterial activity of crude ethanol extract was observed in T. triquatra (brown seaweed) followed by L. optusa (red seaweed) whereas, green seaweed (U. lactuca) showed less antibacterial activity. All the seaweeds crude extracts and their fractions have shown moderate antibacterial activity
Key words: Antibacterial, macroalgae, Turbinaria triquatra, Ulva lactuca, Laurencia optusa, bacterial nosocomial infection
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