Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Regular Article

Application of response surface methodology (RSM) in condition
optimization for essential oil production from Citrus latifolia

Quoc Le Pham Tan*, Xinh Nguyen Thi Kieu, Nguyet Huynh Thi Kim and Xuyen Nguyen Thi Hong.

This research shows the dependence of distillation time and ratio of water/peel on amount of essential oil afterdistilling. Researching and optimizing the factors for essential oil production by laboratory ? scale distillationand the yield was evaluated using the Response Surface Methodology (RSM) with Central Composite FaceCentered(CCF) model. The regression equation obtained was shown below: 2 212 1 2 y = 0.997 - 0.015x + 0.04x - 0.107x - 0.042x .There is the contrast between distillation time and ratio of water/peel with volume of essential oil received.Optimal result is volume of essential oil was 1 ml (y) with quantity of lemon peel/batch of 50g, ratio ofwater/peel (x1) was 6/1, distillation time (x2) in 20 minutes at temperature at 100oC. The essential oil from thepeel of C. latifolia was analysed by GC-MS method. A lot of compounds were identified of which limonene, ??pinene and ??terpinenen were major components. Small amounts of trans-caryophyllene, 4-terpineol, ?-terpinenen?were also detected.

Key words: CCF, C. latifolia, Essential oil, GC-MS, RSM

Full-text options

Full-text Article

American Journal of Diagnostic Imaging


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.