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Original Article

J. Islam. Int. Med. Coll.. 2016; 11(1): 11-15


Vitamin D Status in Diabetic and Non-diabetic Patients of Coronary Artery Disease A Study on Pakistani Population

Aamnah Sajid, Abdul Khaliq Naveed, Amena Rahim, Bilal Sajid.

Abstract
Objective: This cross-sectional observational study was carried out to assess and compare the degree of hypovitaminosis D in diabetic and non-diabetic patients of coronary artery disease in Pakistani population.
Methodology: A total of 149 patients of coronary artery disease were selected in this study. These included 77 male and 72 female patients. There were 75 diabetic and 74 were non-diabetic patients. These participants were assessed for their individual serum vit D levels(ng/ml).Diabetic patients were also questioned about their treatment modalities.
Results: The serum levels of vit D betveen diabetic and non- diabetic patients were 16.4(9.7) ng/ml and 17.4(7.9)ng/ml but the difference was statistically insignificant (p- value 0.4).However vitamin D levels were significantly lower in patients with family history of coronary artery disease (p- value 0.04).
Conclusion:Results of this study did not substantiate the findings of other studies neither any correlation between vit D levels and glucose homeostasis could be investigated.Diabetes mellitus being a multifactorial disease,vitamin D could be a mediator of metabolic disturbances responsible for long-term health outcomes.
Key words: Vit D,VDR,T1DM,T2DM,,Hypovitaminosis D,Islet β cells,Insulin secretion, Insulin sensitivity.

Key words: Vit D,VDR,T1DM,T2DM,,Hypovitaminosis D,Islet β cells,Insulin secretion, Insulin sensitivity.



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