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Original Article

J App Pharm Sci. 2015; 5(6): 070-074


In-vitro Assessment of Effectiveness and Photostability Avobenzone in Cream Formulations by Combination Ethyl Ascorbic acid and alpha Tocopherol Acetate

Marline Abdassah, Ratih Aryani, Emma Surachman, Muchtaridi Muchtaridi.



Abstract
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Avobenzone is UVA sunscreen active substances, which are unstable when exposed to UV radiation, especially UVA. The aim of this study is to to determine the effectiveness and photo stability avobenzone when combined with ethyl ascorbic acid and alpha tocopherol acetate with various concentrations of ethyl ascorbic acid and alpha tocopherol by in vitro using spectrophotometric method. The photostability study of the eight variations of formula showed that the formula 3, 4, 5, 6, 7 and 8 had significant differences with Formula 1 (p

Key words: UVA, SPF (Sun Protecting Factor), erythema transmission, pigmentation transmission

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