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Original Article

J App Pharm Sci. 2015; 5(8): 095-099


Antioxidant and free radical-scavenging properties of seeds flavonoids extract of Cedrus atlantica Manetti, Linum usitatissimum L. and Ocimum basilicum L. species

Fadoua NAIMI, Dalila BOUSTA, Mounyr BALOUIRI, Abdelmalek EL MESKAOUI.



Abstract
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This work aims to evaluate the antioxidant activity of seeds flavonoids extract of Cedrus atlantica Manetti (Pinaceae), Linum usitatissimum.L (Linaceae) and Ocimum basilicum.L (Lamiaceae) species by using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. In DPPH scavenging assay the IC50 value of the extract was found to be respectively 0.40, 1.21 and 0.41 mg.ml-1 while to the IC50 value of the reference standard Butylated hydroxytoluene (BHT) was 0.003 mg.ml-1. The seeds flavonoids extract of C. atlantica Manetti had a strong scavenger power of free radicals. This study suggests that the mean species may act as a providing antioxidant properties and offering effective protection from free radicals. Then, it’s necessary to identify and isolate the compounds that are responsible to the antioxidant activity.

Key words: Keywords: Cedrus atlantica Manetti, Linum usitatissimum.L, Ocimum basilicum.L, Antioxidant activity, Flavonoids, DPPH, BHT.







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