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Pap smear findings in uterine prolapse: a coincidence or indicator for impending malignancy

Hemali J Tailor, Vasudha M Bhagat, Prashant R Patel, Archana Patel, Sonal L Italiya.


Background: Uterine prolapse is a health problem affecting millions of women globally. If left untreated, it can lead to infection, bleeding, metaplasia, and, rarely, cancer.

Objective: To evaluate the Pap smear finding in patients with uterine prolapse and compare it with nonprolapse cases.

Materials and Methods: This was a retrospective study design. Pap smear data of 1,427 patients from January 2012 to December 2012 were analyzed for the history of prolapse and the pap smear findings such as squamous metaplasia, hyperkeratosis, parakeratosis, and reactive cellular changes.

Result: Of 1,427 patients, a total of 233 patients complained different degrees of uterine prolapse, and, in comparison to nonprolapse cases, the pap smear findings of squamous metaplasia, hyperkeratosis, and parakeratosis were statistically significant. Reactive cellular changes were more common in prolapse cases, but the data were not statistically significant.

Conclusion: Uterine prolapse is a health problem affecting millions of women globally. Today, by using an effective test such as pap smear, which is a simple, quick, and painless screening method for early diagnosis and subsequent reduction in the progression to invasive carcinoma, we are now positioned to more effectively evaluate this condition and to enhance our understanding of its outcomes through the pursuit of novel research.

Key words: Pap smear, uterine prolapse, cervical metaplasia

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