Background: Bacteroidales species are predominant in human large intestine, particularly in colon. These microorganisms are able to develop resistance to several antimicrobial drugs. Aim: To determine the resistance profile and presence of genes encoding resistance to metals in intestinal Bacteroidales from children and calves. Methods: Forty four strains were tested. Antimicrobial resistance and presence of resistance genes were evaluated. Resistant strains were submitted to plasmid cure and the susceptibility was tested again. Results: Most of tested strains were resistance to metals and one B. vulgatus (human origin) showed 3.0 kb and 5.0 kb plasmids and one B. vulgatus (animal origin) showed a 4.0 kb plasmid in which the presence of genes czcA, czcB, and czcC was observed. Resistant strains lost the plasmids and resistance to metals was decreased. Conclusions: The presence of genes might be any association with the cadmium resistance. Further studies to characterize the resistance mechanisms or CzcCBA efflux system in Bacteroidales species are necessary.
Bacteroides vulgatus, Resistance to metals, Plasmids, Gene czc