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Review Article

J Pak Dent Assoc. 2019; 28(4): 197-200

Salivary biomarkers of chronic periodontitis

Naima Jabeen,Sarah Ghafoor.


Chronic periodontitis is a slow progressing disease of oral tissue that cause inflammation and bleeding of gingiva. If it is untreated, it leads to periodontal pockets, loosening of teeth and ultimate tooth loss. Saliva is a hypertonic fluid present in the oral cavity that is now being used as a diagnostic tool. Saliva contains water, organic and inorganic molecules that can act as biomarkers for systemic and oral diseases. Presence of these biomarkers in saliva can help in the early detection of chronic periodontitis disease for therapeutic purpose. This review summarizes information regarding salivary biomarkers that can be of help in early detection and diagnosis of chronic periodontitis.

Key words: Chronic periodontitis, salivary biomarkers, systemic diseases, oral diseases.

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