Introduction: Kamsaharitaki Avaleha (KHA) is an important Ayurvedic formulation containing Dashamoola and Haritaki
as main ingredients and Trikatu, Trijata, Yavakshara as the other. Development of new dosage forms without diluting the
basic principles of Ayurveda is the need in current scenario for their global acceptance. Avaleha form has few difficulties
such as problems in transportation, fixing of unit dose, chances of microbial growth etc. Considering these inconveniencies and to convert it into a dose form with additional advantages; an attempt has been made to convert Kamsaharitaki Avaleha into granules and develop preliminary physicochemical profile of both formulations. Materials and Methods: Raw materials have been collected from Pharmacy, Gujarat Ayurved University, Jamnagar, and utili-ed after proper authentication. Avaleha and granules were prepared in Rasashastra and Bhaishajya Kalpana zab, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar. The samples were subjected to relevent physicochemical
parameters. Results: The differences in the physicochemical profile of Kamsaharitaki Avaleha and Kamsaharitaki granules are insignificant. Licrobial count and Heavy metal analysis were within prescribed limits. This indicates Muality and safety of both the products.
Key words: Chromatography, Granules, Kamsaharitaki, Microbial overload, Quality.