Home|Journals|Articles by Year

Directory for Medical Articles
 

Original Research



Evaluation of wound healing potential of methanolic Crinum jagus bulb extract

Sunday Ositadimma Udegbunam, Raphel Okoli Chukwujekwu Kene, Silavanus Maduka Anika, Rita Ijeoma Udegbunam, Theophilus Okafor Nnaji, Madubuike Umunna Anyanwu.


Abstract

Crinum jagus (J. Thomps.) Dandy commonly called Harmattan or St. ChristopherÂ’s lily belonging to the family Lilliaceae is widely used traditionally in Southeastern Nigeria for treatment of skin sores. This study investigated the wound healing potentials of methanolic Crinum jagus bulb extract (MCJBE) using incision, excision and dead space wound healing models. Phytochemical screening showed the presence of alkaloids, glycosides, tannins, saponins in the extract but absence of flavonoids. In the incision and dead space wound models, rats were dosed orally with 300 mg/kg body weight (bw) of 10 and 5% of methanolic Crinum jagus bulb extract (MCJBE) solution, respectively, while in the excision wound model, rats were treated topically with 10 and 5% methanolic Crinum jagus bulb extract ointments (MCJBEO), respectively. The 10% MCJBE gave significantly (p

Key words: Crinum jagus, wound healing, methanolic extract, ointment






Full-text options


Share this Article



Online Article Submission
• ejmanager.com
• ojshosting.net







Do you want to use OJS for your journal ?
work with an experienced partner
www.OJSHosting.net

eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.