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Review Article

Revisiting Mantoux test in the era of immunization and Multi-drug resistant tuberculosis (MDR-TB)

Venkataramana Kandi.

This review reinvents the role of mantoux test/tuberculin skin test (TST) in the laboratory diagnosis of tuberculosis (TB). Tuberculosis has been the most significant infectious disease responsible for severe morbidity and mortality worldwide. Asia and African continents constitute most of the burden of world tuberculosis. Although a treatable infectious disease, the exposed individuals do not always show clinical signs of infection. TB may be present latent in many infected population. Clinical, radiological, cultural and staining methods, molecular techniques and many other advanced laboratory methods are available for the diagnosis of tuberculosis. Among the various laboratory techniques available for the diagnosis of tuberculosis, Mantoux tuberculin skin test is a low cost and easily done test that if performed and interpreted appropriately can be used for diagnosis of TB.

Key words: Mantoux test, Tuberculin skin test (TST), Laboratory diagnosis of Tuberculosis

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