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Case Report



Management of abnormal uterine bleeding caused by leiomyoma in a patient with acute leukemia: a case report

Muhammad Fidel Ganis Siregar.




Abstract

A 19-year-old woman complaining a palpable abdominal mass was admitted with a history of vaginal bleeding 1 month before admission . The patient also experienced gum and nose bleeding with no history of any drug, hormones, or contraceptive use. Sonographical studies of the abdomen and pelvic were suggestive of leiomyoma. Laboratory findings showed leukocytosis (15,800/mm3) with peripheral blood smear revealing a normochromic normocytic anemia state. Bone puncture performed by the hematology division of internal medicine was positive for acute lymphoblastic leukemia. Blood transfusion was performed to treat anemia. Leuprolide acetate (3.75 mg) was injected for three cycles, with an interval of 28 days, to treat leiomyoma. Last follow-up showed that the patient was transferred to the hematology division of internal medicine after complaints of vaginal bleeding resolved on administration of gonadotropin-releasing hormone analog.

Key words: Abnormal uterine bleeding, leiomyoma, leukemia, leuprolide acetate






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