Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

Hepatoprotective and Pancreatoprotective Properties of the Ethanolic Extract of Nigerian Propolis

Ridwan Babatunde Ibrahim, Abdulbasit Amin, Ibrahim Oladayo Mustafa, Ismail Olasile Onanuga, Roehan Olamide Folarin, Wasiu Gbolahan Balogun.

Objective: Increased oxidative stress is associated with the progression of diabetic mellitus. In the present study, we investigated the effects of the ethanolic extract of Nigerian propolis (N. propolis) on markers of oxidative stress, histology of the liver and pancreas and glycaemia in alloxan-induced diabetic rats.
Materials and Methods: Alloxan-induced hyperglycaemic Wistar rats were treated with either metformin (150mg/kg/d) or N. propolis (200mg/kg/d & 300mg/kg/d)) for 28 days. At the end of treatment period, the rats were sacrificed; blood was collected for biochemical analysis while their pancreases and liver were excised and processed for histological studies.
Results: Serum oxidative stress markers and blood glucose concentration were compared between the treated and control rats. In contrast to the non-treated diabetic rats, blood glucose concentration were not significantly different between treated rats and control (P

Key words: liver, pancreas, histology, oxidative stress, lipid profile

Share this Article

American Journal of Physiology, Biochemistry and Pharmacology


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.