Objective: To determine the role of vitamin D in adult-onset asthma by estimating and comparing it with that of healthy controls and to associate it with lung function test.
Methodology: This case control study was conducted in the Department of Physiology, University of Karachi. Cases were recruited from Jinnah Hospital. A total of 280 individuals were categorized into asthmatics and non-asthmatics. History of respiratory illness, D3 intake, drugs that alter serum D3, pregnant and lactating mothers were excluded from study. Asthmatics were included according to GINA guidelines. BMI, Spirometry, and serum 25(OH)2D estimation were performed. Statistically, results were analyzed by SPSS 21.
Results: Difference of BMI and 25(OH)2D between two groups were statistically significant (p
Key words: Asthmatics, Immune-modulatory, inflammation, spirometry, Vitamin D, insufficiency.
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