Home|Journals|Articles by Year|Audio Abstracts
 

Case Report



A case of cancer of unknown primary origin without a primary site

Ratna Bulusu.




Abstract

About 3% of all patients with cancer have cancer of unknown primary origin (CUP). This study is on a patient who reported for a gynecologic checkup as she was on tamoxifen and noted to have metastatic lesions at multiple sites including pelvis, uterus, tubes, and ovaries. The case presented is interesting as the patient has no primary site of carcinoma of breast, but PET–CT scans and advanced immunohistochemistry techniques used for the metastatic tissue showed strong positivity to breast carcinoma. Various intensive tests were needed to diagnose the primary site without a lesion. Also, the patient received the first-line chemotherapy, multiple transfusions, debulking surgery, and then the second-line chemotherapy. With a poorly differentiated carcinoma spread all over the skeletal system, gut, abdomen, and pelvis, the patient tolerated the second-line chemotherapy also and is still surviving 2 years after the detection of CUP.

Key words: Carcinoma of unknown primary origin, positron emission tomography, 18 F-fluorodeoxyglucose, immunohistochemistry, debulking surgery






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.