Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Original Research



Potential Role of Oxidized LDL (ox-LDL) and Adhesion Molecules (VCAM-1, ICAM-1) in Type 2 Diabetes Mellitus Patients in Qassim region, KSA

Manal Basyouni, Maha Ahmed, Hisham Ismail, Iman Esmat.

Abstract
Background: Type-2 diabetes mellitus (type 2 DM) is powerful and independent risk factors for coronary artery disease, stroke, and peripheral arterial disease. Accelerated atherosclerosis is the major vascular complication of diabetes, constituting the main cause of morbidity and mortality in this common metabolic disorder. The role of oxidized low density lipoprotein (Ox-LDL) and cell adhesion molecules (CAMs) in diabetic complications as atherogenesis is unclear and available studies are contradictory.
Objectives: The current study was conducted to investigate the pathological role of oxLDL and cell adhesion molecules (VCAM-1 and ICAM-1) and their clinical impact in type 2 DM patients.
Patients and Methods: The serum levels of ox-LDL and VCAM-1 and ICAM-1 were measured by enzyme-linked immunosorbent assay. Their levels were correlated to glycemic status and lipid profile in 60 type 2 diabetic patients compared to 25 healthy subjects.
Results: The current study revealed a significant higher ox-LDL and VCAM-1 levels in diabetic patients compared to healthy group, with significant higher levels of oxLDL in uncontrolled diabetes compared to controlled diabetes. The elevation of ox-LDL in DM patients (p

Key words: Type 2 Diabetes Mellitus, Oxidized LDL, Intercellular adhesion molecule-1 (ICAM-1) and Vascular Cell Adhesion Molecule-1 (VCAM-1)



Similar Articles

Using the Health Belief Model to examine travelers' willingness to vaccinate and support for vaccination requirements prior to travel.
Suess C, Maddock J, Dogru T, Mody M, Lee S
Tourism management. 2022; 88(): 104405

Exploring the Alzheimer's disease neuroepigenome: recent advances and future trends.
Zhang H, Elefant F
Neural regeneration research. 2022; 17(2): 325-327

Environmental stocks, CEO health risk and COVID-19.
Fernández-Méndez C, Pathan S
Research in international business and finance. 2022; 59(): 101509

Emerging roles of NRBF2/PI3KC3 axis in maintaining homeostasis of brain and guts.
Wu MY, Cai CZ, Yang C, Yue Z, Chen Y, Bian ZX, Li M, Lu JH
Neural regeneration research. 2022; 17(2): 323-324

Presenilin mutations and their impact on neuronal differentiation in Alzheimer's disease.
Hernandez-Sapiens MA, Reza-Zaldívar EE, Márquez-Aguirre AL, Gómez-Pinedo U, Matias-Guiu J, Cevallos RR, Mateos-Díaz JC, Sánchez-González VJ, Canales-Aguirre AA
Neural regeneration research. 2022; 17(1): 31-37


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites