Home|Journals|Articles by Year|Audio Abstracts

Directory for Medical Articles
 

Original Research



Comparative Study of Iron status between Toxemia of pregnancy and Normal pregnancy

Dr. Aruna Kumari Bandaru.




Abstract

Objective: Comparison of iron parameters in toxemia of pregnancy with controls and their role in etiology, pathogenesis, fetal outcome, and maternal complications.
Materials and method: This study was conducted on hundred pregnant women between 20 to 35 yrs age group during third trimester. Sixty were identified as toxemia of pregnancy and forty matched healthy pregnant women were taken as controls in the study. Iron parameters were analyzed and evaluated the role of iron in high risk pregnancies.
Results: Of the 60 toxemia of pregnancy patients enrolled in the study, 35 (58.3%) were classified as preeclampsia and 25 (41.7%) were classified as eclampsia. There was significantly increased serum iron, ferritin, % saturation of transferrin in toxemia of pregnancy than in controls, but unsaturated iron binding capacity (UIBC) was significantly decreased in toxemia of pregnancy than in controls. Total iron binding capacity (TIBC) and transferrin did not differ much significantly in both the groups. 20% of preeclampsia and all (100%) eclampsia has higher % saturation of transferrin levels (>60-100%).
Conclusion: Iron status of all pregnant women should be assessed before giving the iron supplements as they cause more harm than benefit. The estimation of iron parameters particularly ferritin, % saturation of transferrin and UIBC are useful markers to predict prognosis, severity of liver damage and emergence of HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in toxemia of pregnancy especially in eclampsia, as iron species implicated in the etiology of toxemia of pregnancy likely to increase oxidative stress and promote the endothelial cell damage.

Key words: key words: Toxemia of pregnancy; preeclampsia; eclampsia; iron; ferritin; % saturation of transferrin (%Tf); unsaturated iron binding capacity( UIBC); total iron binding capacity (TIBC).






Full-text options


Share this Article



Online Article Submission
• ejmanager.com
• ojshosting.net







Do you want to use OJS for your journal ?
work with an experienced partner
www.OJSHosting.net

eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.