Systemic lupus erythematosus (SLE) is a common autoimmune disease with the prevalence of 3.2 per 100000 in India. The reported association of SLE and thyroid disorders varies as much as 3.9 24 %. Here we present a 22 year old female with complaints of breathlessness, fatigue, myalgia, fever and decreased urine output since 2 days, who was brought to Medicine OPD, Wenlock District Hospital, Mangalore, with a past history of SLE on irregular treatment and follow up since 2 years. On examination she had pallor, generalized oedema, BP 170/90 mm Hg, ejection systolic murmur in pulmonary area. Investigatory findings were positive for ANA and anti TPOand also were suggestive of anaemia, hypothyroidism and nephropathy.
Key words: SLE (Systemic Lupus Erythematosus), ANA (Antinuclear Antibody), anti TPO (Anti Thyroid Peroxidase)
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