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Effect of Sperm Count on Success of Intrauterine Insemination in Couples Diagnosed with Male Factor Infertility

Erhong Zhang, Xin Tao, Weijie Xing, Liuhong Cai, Bin Zhang.


Objective: To exam semen parameters in predicting intrauterine insemination (IUI) outcomes in couples with male factor. Study design: This retrospective study was performed at department of infertility and sexual medicine from September 2007 to February 2014. 307 couples with male factor infertility were included and 672 IUI cycles were analyzed. Results: From 672 inseminations performed on 307 couples, there are 27.36% couples get pregnancy (84 out of 307) and the overall pregnancy rate was 12.95% (87 out of 672) of IUI. With the increase of post total progressive sperm count, the clinical pregnancy rate increased. When the initial progressive sperm count was lower than 5*106, there was no pregnant in the IUI cycle. At the end of the third cycle, 85 clinical pregnancies had been achieved (97.70%). Conclusions: The initial total progressive sperm count lower than 5*106 means the poor outcome of IUI in the infertile couples with male factor. If the infertile couples with male factor don’t get pregnancy after three IUI cycles, the couples should receive re-assessment or other artificial reproductive technology.

Key words: Intrauterine insemination; Male factor infertility; Semen analysis.

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