Membrane Integrity of Two Human Erythrocyte Genotypes in The Presence of Aqueous Solution of Sodium Metabisulphite and Their Correlations In Vitro. -

A J Physiol Biochem Pharmacol. 2014; 3(4): 164-169

doi: 10.5455/jib.20141030112431

Paul Chidoka Chikezie.

Abstract
Erythrocyte membrane integrity is a pre-requisite for cellular functionality. The present study sought to investigate the capacity of normal adult haemoglobin (HbAA) and homozygote haemoglobin S (HbSS) erythrocytes to withstand osmotic stress when incubated over time (0 h ≤ t ≤ 8 h) in relatively low concentrations of Na2S2O5 Key words: Erythrocytes, genotypes, malondialdehyde, mean corpuscular fragility, sodium metabisulphite.

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