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Anti-conjunctivitis effect of fresh juice of xGraptoveria (Crassulaceae) – a phytochemical and ethnobotanical study

Nadezhda Markova, Daniela Batovska, Ekaterina Kozuharova, Venelin Enchev.


The aim of this preliminary study is to test the anti-conjunctivitis properties of xGraptoveria (Crassulaceae) and to identify its bioactive constituents.
Fresh watery juice of leaves of xGraptoveria was extracted with n-butanol and the extract was analyzed by GC/MS. The ethnobotanical appraisal of the anti-conjunctivitis properties of xGraptoveria was based on 11 interviews about the symptoms against which this plant demonstrated positive effect.
Fresh juice of xGraptoveria leaves applied directly to the irritated eye two times per day cured conjunctivitis in all reported cases.
In this preliminary study it is suggested that xGraptoveria exerts anti-conjunctivitis activity, via synergistic effect of different chemical compounds, most probably alkylamines and mainly hydroxycarboxylic, aliphatic and aromatic carboxylic acids.

Key words: xGraptoveria leaf juice, conjunctivitis, ethnobotanical, alkylamines, GC/MS

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