Abstract

Background: ABO blood groups have been associated with various disease phenotypes, particularly cardiovascular diseases. The
analysis of the heart rate variability (HRV) signal is an important tool for studying the autonomic nervous system.

Aims & Objectives: The present study was designed to find out the association between different A, B, O blood groups and HRV in
normal individuals.

Materials and Methods: This cross sectional study included 120 volunteered healthy medical students. The subjects were grouped
into four groups A, B, AB and O. HRV was analyzed by using time domain and frequency domain method during normal breathing at
rest for five minutes. HRV was also analyzed during deep breathing for one minute using time domain method.

Results: The analysis of HRV showed that during normal breathing, there was no statistically significant difference (P>0.05) in HRV
among the ABO blood groups. HRV during deep breathing showed that there was a statistically significant increase in SDNN value
(P

Key words: Blood Groups; Heart Rate Variability; Time Domain Analysis; Frequency Domain Analysis; Standard Deviation of NN Intervals (SDNN)