Abstract

This study aimed to systematically evaluate the evidence respecting the association of risk factors for the development of cardiovascular disease (CVD) among patients with diabetes and hypertension (HTN). Articles were searched from 2015 to 2022 through PubMed, MEDLINE, and Embase. The inclusion criteria included risk factors such as hemoglobin A1c (HbA1c), blood pressure measurement, body mass index, determining the glomerular filtration rate(GER), and blood lipid profile in patients with HTN and diabetes. The quality of the study was assessed by assessment Newcastle-Ottawa scale (NOS). After thorough research, only seven out of 170 articles were selected. The systolic blood pressure (SBP) and GER were calculated. All studies’ quality was good under the NOS criteria. Generally, high HbA1c: 138 mmHg, high or low GFR: >60 ml/minute/1.75 m2), and increasing SBP (SBP from 120 to 139 to ≥140 mmHg) are great risk factors for CVD among diabetes and HTN patients. No data on blood lipid profile and body mass index was available among the selected studies. It was concluded that relatively well-controlled HTN and diabetes might reduce the risk factors for the development of CVD.

Key words: Cardiovascular diseases, diabetes, hypertension, impact, systemic review.