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Pattern of thyroid disorder in thyroidectomy specimen

Ashwini Kolur, Anitha B, Letha P, Trupti Joshi, Jayasree, Samith Ahmed, Harish Naik.


Abstract

Background: There is enormous burden of thyroid diseases in the general population. Among all the endocrine disorders, thyroid
disorder are the most common in India, though most of them are benign. Multinodular goitre is the commonest cause of thyroid enlargement followed by thyroid tumors.

Aims & Objectives: The aim of this study is to describe the clinicopathological findings of thyroidectomy specimens.

Materials and Methods: It was a 24 month (May 2012 to May 2014) non-interventional retrospective study, including all cases of
thyroidectomy specimens in Azeezia Medical College, Kollam, Kerala. All histology reports, clinical information and stained slides were reviewed. Thyroid diseases were grouped into different categories according to gender and age distribution.

Results: A total of 179 lesions were reviewed, 167 were from females and 12 from males. 164 cases were found non-neoplastic and
15 were neoplastic lesions. Multinodular goitre was found to be the commonest - 116 (64.8%) non-neoplastic lesion, followed by Hashimoto’s thyroiditis 21(11.73%). Among 179 specimens, 15 (8.37%) were of thyroid malignancy, and papillary carcinoma was found to be the commonest malignant thyroid lesion, observed in (10 /15) 66.66% of all thyroid malignant lesions. This was followed by follicular carcinoma (3/15) 20% and while medullary and poorly differentiated carcinoma were noted in one patients each.

Conclusion: The commonest cause of goitre was multinodular goitre. Papillary carcinoma was the commonest malignant lesion.

Key words: Multinodular goiter, Follicular adenoma, Hashimoto’s thyroiditis, Papillary carcinoma.






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