Abstract

Methemoglobinemia, an important and potentially life-threatening manifestation of Dapsone poisoning. With the increasing use of dapsone for various indications, acute poisoning (either accidental ingestion or suicidal) is increasingly recognized. We report a case of an eighteen year old female presented to the emergency room with alleged history of consumption of about 150 tablets of Dapsone (about six hours after ingestion) and managed successfully. Dapsone is a com¬monly used drug in the treatment of leprosy and many other conditions and an overdose of Dapsone can be a potential cause of methemoglobinemia. Prompt diagnosis of Dapsone induced methemoglobinemia and aggressive management of these patients results in good outcome.

Key words: Dapsone, dapsone poisoning, cyanosis, methaemoglobin, poisoning