Dejerine-Roussy syndrome, also known as the ‘thalamic pain syndrome’ is a condition in which the body becomes hypersensitive to pain as a result of damage to the thalamus, a part of the brain that affects sensation. The Dejerine Roussy syndrome can occur in 2-6% of post-stroke patients. Pain is described as "burning" or "freezing," and is
often accompanied by sensory disturbances, especially those of temperature.
Pathophysiology appears to involve lesions of the spinothalamic pathyways
with disinhibition and excitation of NMDA receptors in the thalamus.
Dejerine Roussy syndrome, Thalamic pain syndrome, Post stroke pain syndrome