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Anti-inflammatory activity of Russelia equisetiformis Schlecht & Cham: identification of its active constituent

Awe Emmanuel Olorunju, Adeloye Adewale, Makinde Janet Modupe.

Cited by (2)

Abstract
Aim: The present research work was carried out to isolate and identify the chemical constituent responsible for the antinflammatory activity of Russelia equisetiformis.
Method: Isolation was carried out using column chromatography. The structure of the isolated compound was identified and established using the available spectroscopic techniques including high-resolution electron mass spectrum. The anti-inflammatory activity was evaluated using egg albumin-induced paw edema, formaldehyde–induced arthritis and cotton pellet granuloma in-vivo tests. Prednisolone was used as a standard drug.
Results: Lupeol was isolated as colorless crystals (mp 213-215OC).Lupeol at the doses of 10, 20, 40 mg/kg produced significant (P

Key words: Russelia equisetiformis, Scrophulariacae, lupeol isolation, Anti-inflammatory activity


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The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
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