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Thyroid lesions: Sonological, cytological, and histopathological correlation: A 3-year experience

Ashok Yadav, Pankaj Yadav, C V Kulkarni, N P Tiwari.


Background: Thyroid is a superficial, readily accessible endocrine gland. Differentiation between nonneoplastic and neoplastic thyroid disease is not difficult. Accurate subtyping and grading of thyroid neoplasms are possible only with the combined efforts of sonologists and pathologists. With its increasing use, it is evident that ultrasonography (USG) is becoming more and more reliable as a predictor of the exact nature of neoplastic thyroid lesions.

Aims and Objectives: (1) To try and establish a correlation between the various sonography vs cytology, histopathology, and cytology plus histopathology findings. (2) To evaluate and compare the results of USG, fine-needle aspiration cytology (FNAC), and postoperative histopathology examination. (3) To detect any emerging trend in relation with the USG and histopathology and cytology findings.

Materials and Methods: Retrospective data were obtained from the Departments of Radiodiagnosis and Pathology of Mahatma Gandhi Memorial Medical College, Indore, Madhya Pradesh, India. The time frame of the study was 3 years in which 262 cases were considered.

Results: In this study, USG was found to emerge as a potent diagnostic modality to predict the exact nature of thyroid lesions. The results indicate that approximately 270% increase was found in the use of USG. At the same time, there is 250% increase was also found in the use of FNAC.

Conclusion: An accurate correlation (90%) between the USG and FNAC findings was found in nonneoplastic lesions (inflammatory and cystic). Histopathology remains a gold standard.

Key words: Sonography; Cytology; Histopathology; Thyroid Lesions

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