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Case Report

J Pak Med Assoc. 2014; 64(6): 705-707

Two cases of Creutzfeldt-Jakob Disease from an ongoing dementia registry in Pakistan

Arsalan Ahmad, Faiza Rao, Sahrish Aieshah.

Creutzfeldt-Jakob disease (CJD) is a rare prion disease that
leads to a rapidly progressive dementia (RPD) and
associated neurological features. It is not well
documented in our country; therefore its true prevalence
in Pakistan is not known. Here we report two cases of
sporadic probable CJD seen in our hospital. The first, a 62
years old female, presented with RPD and myoclonus. The
second was a 72 years old female who presented with
generalized axial and limb rigidity, mutisim, personality
changes and hallucinations along with RPD. Both cases
were diagnosed as CJD on the basis of clinical, MRI and
EEG findings.

Key words: CJD, Pakistan, Rapidly progressive dementia (RPD).

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