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A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients

Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar.




Abstract
Cited by (1)

Background: Derangement of gonadal functions has been reported in association with HIV infection, but data from Indian population are not sufficient.

Aims & Objective: To evaluate the effect of highly active antiretroviral therapy (HAART) on the gonadal dysfunction in male HIV patients.

Materials and Methods: A total of 45 male HIV-positive patients were included and divided in two groups on the basis of CD4 cell count. Patients in groups A and B had CD4 count ≤200 and >200 cell/μL, respectively. Baseline hormone level was measured before the start of HAART, and the patients were followed up for 6 months and the hormone levels were measured again.

Results: In group A (n = 29), six (20.69%) patients had testosterone level

Key words: Highly Active Antiretroviral Therapy (HAART); Human Immunodeficiency Virus (HIV); Endocrine Changes






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