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Original Article

J Pak Med Assoc. 2014; 64(6): 653-659

Safety of primary percutaneous coronary intervention with and without (selective) thrombus aspiration.

Muhammad Tariq Farman, Tahir Saghir,Nadeem Hasan Rizvi, Jawaid Akbar Sial, Naveedullah Khan, Abdul Malik, Khan Shah Zaman.

Objective: To determine the safety and efficacy of selective thrombus aspiration during Primary Percutaneous
Coronary Intervention (PCI).
Methods: This observational prospective study was conducted in the catheterization laboratory of a tertiary care
cardiovascular centre. A total of 150 consecutive patients who underwent primary PCI were enrolled. Aspiration was
done only when thrombus burden was considered significant. After completion of procedure angiographic and
electrocardiographic signs were recorded and clinical follow up was documented up to 1 year.
Results: No significant difference among the groups was found in age, height, weight and other risk factors like
Hypertension, Diabetes Mellitus and Smoking. In general, left anterior descending artery was culprit in ~ 65 % of
patients and more than 90 % of culprit vessels had visible thrombus. Multivessel disease was present in 38 % of
patients and 22.7% had past history of myocardial infarction. Out of 150 patients 117 (78%) underwent thrombus
aspiration. No significant difference was found in ST resolution within 60 minutes (72.6 vs 81.8 %; P

Key words: Acute ST elevation myocardial infarction, Priamry percutaneous coronary intervention, Aspiration thrombectomy.

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