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Vitamin D level and body mass index in patients with type II diabetes mellitus

Kanchana R, Pushpa K.

Abstract
Background: There are many evidence suggesting an association between Vitamin D and diabetes mellitus. Low Vitamin D levels, development of diabetes mellitus, and metabolic syndrome have all been interrelated. Interestingly, obesity and sedentary lifestyle are risk factors common to both Vitamin D deficiency and diabetes mellitus.

Aims and Objectives: The study was carried out to determine the correlation of Vitamin D levels and body mass index (BMI) in patients with type 2 diabetes mellitus (T2DM).

Materials and Methods: A case-controlled study was carried out at Shree Balaji Medical College and Hospital, Chrompet, Chennai, a tertiary care teaching institute. A total of 48 patients with T2DM (cases) and 43 non-diabetics healthy individuals (controls) were included in this study. The controls were age and sex matched with the cases. The demographic data and other relevant information were recorded in case record form. 5 mL blood was collected from all persons in the fasting state and analyzed for plasma blood glucose levels and Vitamin D. Plasma glucose levels were determined by glucose oxidase- peroxidase method. Vitamin D levels were determined by ELISA method.

Results: An inverse correlation has been found between Vitamin D and BMI in diabetics. ANOVA single factor done for diabetics and non-diabetics both cases F statistical value >F critical value and P < 0.05 proving statistical significance. As Vitamin D levels decreased, there was an increase in plasma blood glucose levels.

Conclusion: It was thus concluded that Vitamin D supplementation can help in efficient control of blood glucose levels in diabetes as well as prevent early onset of diabetes in obese individuals.

Key words: Type 2 Diabetes Mellitus; Vitamin D; Body Mass Index; Hypovitaminosis D


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